Papers by May Dongmei Wang
MedAdapter: Efficient Test-Time Adaptation of Large Language Models Towards Medical Reasoning (2024.emnlp-main)
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| Challenge: | Large language models (LLMs) have improved generation and reasoning capabilities compared to traditional BERT-sized models due to massive number of parameters and extensive pre-training on vast textual corpora. |
| Approach: | They propose a unified post-hoc adapter for test-time adaptation of large language models . they propose to fine-tune only a small BERT-sized adapter to rank candidate LLMs . |
| Outcome: | The proposed adapter improves performance on four biomedical tasks without requiring computational resources or sharing data with third parties. |
BMRetriever: Tuning Large Language Models as Better Biomedical Text Retrievers (2024.emnlp-main)
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Ran Xu, Wenqi Shi, Yue Yu, Yuchen Zhuang, Yanqiao Zhu, May Dongmei Wang, Joyce Ho, Chao Zhang, Carl Yang
| Challenge: | Developing effective biomedical retrieval models is important for excelling at knowledge-intensive biomedically tasks but still challenging due to the lack of sufficient publicly annotated biomedic data and computational resources. |
| Approach: | They propose a series of dense retrievers for enhancing biomedical retrieval via unsupervised pre-training on large biomedically corpora, followed by instruction fine-tuning on a combination of labeled datasets and synthetic pairs. |
| Outcome: | Experiments on 5 biomedical tasks across 11 datasets confirm the performance of the retrieval model on various biomedically demanding tasks. |
EHRAgent: Code Empowers Large Language Models for Few-shot Complex Tabular Reasoning on Electronic Health Records (2024.emnlp-main)
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Wenqi Shi, Ran Xu, Yuchen Zhuang, Yue Yu, Jieyu Zhang, Hang Wu, Yuanda Zhu, Joyce Ho, Carl Yang, May Dongmei Wang
| Challenge: | EHRAgent enables clinicians to interact with EHRs using natural language . reliance on rule-based conversion systems often necessitates additional training or effort from data engineers. |
| Approach: | They propose a large language model agent that generates and executes code in natural language to facilitate clinicians in directly interacting with EHRs. |
| Outcome: | The proposed agent outperforms the strongest baseline by up to 29.6% in success rate on three real-world EHR datasets. |
Tree-of-Evidence: Efficient "System 2" Search for Faithful Multimodal Grounding (2026.findings-acl)
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| Challenge: | Attention-based methods fail to faithfully represent the model’s decision process when integrating heterogeneous modalities. |
| Approach: | They propose an inference-time search algorithm that frames interpretability as a discrete optimization problem. |
| Outcome: | The proposed algorithm retains over 98% of full-model AUROC with as few as five evidence units and achieves higher decision agreement and lower error than LIME, SHAP, saliency, and concept-bottleneck baselines under sparse budgets. |
Knowledge-Infused Prompting: Assessing and Advancing Clinical Text Data Generation with Large Language Models (2024.findings-acl)
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Ran Xu, Hejie Cui, Yue Yu, Xuan Kan, Wenqi Shi, Yuchen Zhuang, May Dongmei Wang, Wei Jin, Joyce Ho, Carl Yang
| Challenge: | Clinical natural language processing (NLP) is a subfield that requires the extraction, analysis, and interpretation of unstructured clinical text. |
| Approach: | They propose a model which infuses knowledge into clinical text generation with LLMs for clinical NLP tasks. |
| Outcome: | The proposed model improves performance across 8 clinical NLP tasks and 18 datasets by 7.7%-8.7% on average. |
RAM-EHR: Retrieval Augmentation Meets Clinical Predictions on Electronic Health Records (2024.acl-short)
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| Challenge: | Existing deep learning models for EHRs rely on knowledge from a single source and do not capture the semantic information for medical codes. |
| Approach: | They propose a Retrieval AugMentation pipeline to augment clinical prediction on EHRs . they use multiple knowledge sources to convert them into text and use consistency regularization to capture complementary information from patient visits and summarized knowledge. |
| Outcome: | Experiments on two EHR datasets show that RAM-EHR improves clinical prediction tasks. |
MetaBench: A Multi-task Benchmark for Assessing LLMs in Metabolomics (2026.acl-long)
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Yuxing Lu, Xukai Zhao, J. Ben Tamo, Micky C. Nnamdi, Rui Peng, Shuang Zeng, Xingyu Hu, Jinzhuo Wang, May Dongmei Wang
| Challenge: | Large Language Models (LLMs) have demonstrated remarkable capabilities on general text, but their proficiency in specialized scientific domains remains uncharacterized. |
| Approach: | They evaluate the capabilities of large language models in metabolomics research using MetaBench . they found that models perform well on text generation tasks, but cross-database identifier grounding remains challenging . |
| Outcome: | The evaluation of 25 open- and closed-source LLMs reveals distinct performance patterns across metabolomics tasks. |